Nā huahana
6-Amino-1-methyluracil
Synonyms:6-Amino-1-methyl-1H-pyrimidine-2,4-dione;2,4(1H,3H)-Pyrimidinedione,6-amino-1-methyl-;Uracil,6-amino-1-methyl- (7CI,8CI);1-Methyl-6-aminouracil;
Waiwai Kemika o 6-Amino-1-methyluracil
● Ke ʻano / kala: ʻaneʻane keʻokeʻo i ka pauka crystalline beige iki
● Lae hehee:300 °C
● Hōʻike Hōʻikeʻike:1.548
● PKA:9.26±0.40(Wanamua)
● PSA：80.88000
● Māmā:1.339 g/cm3
● LogP:-0.76300
● Waihona Temp.: E mālama i kahi pōʻeleʻele, Inert ea, lumi wela
● Solubility.:Soluble in diluted sodium hydroxide solution.
● XLogP3:-1.3
● Ka helu o ka mea hāʻawi i ka hydrogen Bond:2
● Ka helu ʻana o ka mea hoʻopaʻa hydrogen:3
● Ka helu paʻa hiki ke hoʻololi:0
● Nuipa pololei:141.053826475
● Helu Atoma Kaumaha:10
● Paʻakikī:221
Maʻemaʻe/Maʻemaʻe
99%, *ʻikepili mai nā mea hoʻolako maka
6-Amino-1-methyluracil *ʻikepili mai nā mea hoʻolako reagent
ʻIkepili palekana
● Piktogram(s):
● Nā Code Hazard:Xn
● Nā ʻōlelo: 22-36/37/38
● Olelo Hoomalu:26
Nā waihona MSDS
Pono
● Canonical SMILES: CN1C(=CC(=O)NC1=O)N
● Hoʻohana: 6-Amino-1-methyluracil ua ʻike ʻia e hoʻohana i nā hopena pale i ka DNA repair glycosylase.Ua ʻike ʻia hoʻi e hoʻohana ʻia ma ke ʻano he pale ahi.Hiki ke hoʻohana ʻia ka 6-Amino-1-methyluracil i ka hoʻomākaukau ʻana i ka 1,1?-di methyl-1H-spiro[pyrimido[4,5-b]quinoline-5,5?-pyrrolo[2,3-d]pyrimidine ]-2,2?,4,4?,6?(1?H,3H,3?H,7?H,1?H)-pentaone, ma o ka hoʻopili ʻana me isatin i mua o ka catalytic p-toluene sulfonic acid .
ʻO 6-Amino-1-methyluracil, ʻike ʻia hoʻi ʻo Adenine a i ʻole 6-Aminopurine, he mea hoʻohuihui kūlohelohe me ke ʻano kemika C5H6N6O.He purine derivative a he ʻāpana o nā waikawa nucleic.ʻO Adenine kekahi o nā nucleobase ʻehā i loaʻa ma DNA a me RNA, me ka cytosine, guanine, a me thymine (ma DNA) a i ʻole uracil (ma RNA).Hoʻopili ia me thymine (i loko o ka DNA) a i ʻole uracil (i ka RNA) ma o ka hoʻopaʻa ʻana i ka hydrogen, e hana ana i hoʻokahi o nā paʻa kumu i hoʻokumu i ke ʻano helix pālua o DNA. kaʻina hana.Hoʻohana ia ma ke ʻano he ʻāpana o nā cofactors e like me NADH, NADPH, a me FAD, i komo i loko o nā hopena enzymatic like ʻole.Hoʻohana pū ʻia ʻo Adenine i ka synthesis o nā molekole koʻikoʻi e like me ATP (adenosine triphosphate), i ʻike ʻia ʻo "ke kālā ikehu" o ke kelepona. hoʻohuihui.Loaʻa i ka ʻoihana a hoʻohana nui ʻia i ka noiʻi ʻepekema, nā noiʻi lapaʻau, a me ka ʻoihana lāʻau.He mea nui hoʻi e mālama pono i ka adenine i mea e pale ai i ka hōʻino a mālama i kona kūpaʻa.
