Nā huahana
2,4-Diamino-6-hydroxypyrimidine
Hydroxypyrimidine mau waiwai
| Lae hehee | 285-286 °C (Dek.) (kumu) |
| Lae paila | 234.22°C (manaʻo koʻikoʻi) |
| mānoanoa | 1.3659 (manaʻo koʻikoʻi) |
| hōʻike hoʻopaʻa ʻana | 1.7990 (manaʻo) |
| ka mahana mālama. | E mālama i kahi pōʻeleʻele, Inert ea, lumi wela |
| hikiwawe | DMSO (Lili iki), Methanol (Lili iki) |
| pka | 10.61±0.50(Wanamua) |
| ʻano | Pauda Crystalline maikaʻi |
| kala kala | Keʻokeʻo i ka cream |
| Pilikino | Māmā Māmā |
| ʻO Merck | 14,2981 |
| BRN | 125006 |
| InChIKey | SWELIMKTDYHAOY-UHFFFAOYSA-N |
| ʻIkepili ʻikepili CAS | 56-06-4(Hōʻikeʻikepili CAS) |
| NIST Chemistry Reference | 4(1H)-pyrimidinone, 2,6-diamino-(56-06-4) |
| Pūnaehana Kakau Lapaʻau EPA | 2,6-Diamino-4(1H)-pyrimidinone (56-06-4) |
Hydroxypyrimidine wehewehe huahana
ʻO 2,4-Diamino-6-hydroxypyrimidine he mea hoʻohui kemika me ke ʻano mole mole C4H6N4O.He mea hoʻohuihui ia no ka ʻohana pyrimidine.ʻO ka pūhui he pyrimidine apo, ʻelua mau pūʻulu amino (NH2) i hoʻohui ʻia ma ke kūlana 2 a me 4-kūlana, a hoʻopili ʻia kahi hui hydroxyl (OH) ma ke kūlana 6.Hiki ke hōʻike ʻia ke ʻano kemika e like me: Ammonia ||H--C--C--C--N--C--C--NH2 ||oh 2,4-Diamino-6-hydroxypyrimidine nā noi like ʻole i ka ʻoihana lāʻau.He mea koʻikoʻi koʻikoʻi ia i ka synthesis o nā lāʻau lapaʻau he nui, me nā lāʻau antiviral a me antitumor.Hoʻohana ʻia ia e hana i nā analog nucleotide i hoʻohana ʻia i ka noiʻi lāʻau lapaʻau.
Ma kahi o nā noi lāʻau lapaʻau, hoʻohana ʻia ʻo 2,4-diamino-6-hydroxypyrimidine ma ke ʻano he mea hoʻohui i nā agrochemical.He mea nui ia i ka synthesis o nā mea hoʻoponopono ulu a me nā fungicides.He mea nui e hahai i kahi protocol palekana kūpono i ka wā e hoʻohana ai i ka 2,4-diamino-6-hydroxypyrimidine.No ka mea ua hoʻokaʻawale ʻia ʻo ia ma ke ʻano he mea hoʻonāukiuki kemika, pono e mālama ʻia me ka mālama pono a pono e hoʻohana pono i nā lako pale pilikino e pale aku ai i ka pilina pololei.
I ka hōʻuluʻulu ʻana, ʻo 2,4-diamino-6-hydroxypyrimidine kahi hui kūlohelohe me nā noi i ka lāʻau lapaʻau a me ka mahiʻai.Hoʻohana ʻia kona ʻano kemika ma ke ʻano he waena i ka synthesis o nā lāʻau lapaʻau a me nā mea hoʻoponopono ulu ulu.
ʻIke palekana
| Nā Code Hazard | Xi |
| Nā ʻŌlelo Hoʻopilikia | 36/37/38 |
| Nā ʻōlelo palekana | 22-24/25-36-26 |
| WGK Kelemānia | 3 |
| Nānā Hazard | Hoʻonanea |
| TSCA | ʻAe |
| HS Code | 29335995 |
Hydroxypyrimidine ka hoʻohana a me ka Synthesis
| wehewehe | ʻO ka 2,4-Diamino-6-hydroxypyrimidine (DAHP) he mea hoʻopaneʻe kūikawā o GTP cyclohydrolase I, ka pae palena palena no ka synthesis de novo pterin.Ma nā pūnaewele HUVEC, ʻo ka IC50no ke kaohi ana i ka BH4ʻO ka biosynthesis ma kahi o 0.3 mM.Hiki ke hoʻohana ʻia ka DAHP e ālai pono i ka hana NO ma nā ʻano kelepona. |
| Na Waiwai Kemika | Paʻa Keʻokeʻo |
| Hoʻohana | ʻO ka 2,4-Diamino-6-hydroxypyrimidine (DAHP) he mea hoʻopaneʻe kūikawā o GTP cyclohydrolase I, ka pae palena palena no ka synthesis de novo pterin.Ma nā pūnaewele HUVEC, ʻo ka IC50 no ka pale ʻana i ka biosynthesis BH4 ma kahi o 0.3 mM.Hiki ke hoʻohana ʻia ka DAHP no ka pale pono ʻana i ka hana NO ma nā ʻano kelepona he nui.[Cayman Chemical] |
| Hoʻohana | Aia ia ma ka hoʻomaka ʻana o ka enzyme-catalyzed cascade e hoʻomaka me kēia ʻāpala kalapona ʻehiku a hoʻopau ʻia me nā amino acids phenylalanine, tyrosine, a me tryptophan. |
| Hoʻohana | ʻO 2,4-Diamino-6-hydroxypyrimidine (cas # 56-06-4) he mea hoʻohui pono i ka synthesis organik. |
| Na Hana Hoomaemae | Hoʻopili hou ia mai H2O.[Beilstein 25 III/IV 3642.] |
