Nā huahana
2,4-Diamino-6-hydroxypyrimidine 2,6-Diamino-4-Hydroxyprimidine
Nā mea like: 4(1H)-Pyrimidinone,2,6-diamino- (8CI,9CI);2,4-Diamino-6-hydroxypyrimidine;2,4-Diamino-6-pyrimidinone;2,6-Diamino-3,4 -dihydropyrimidin-4-one;2,6-Diamino-4(1H)-pyrimidinone;2,6-Diamino-4(3H)-pyrimidinone;2,6-Diamino-4-hydroxypyrimidine;2,6-Diamino-4 -pyrimidinol;2,6-Diaminopyrimidin-4-one;2,6-Diaminopyrimidine-4(3H)-one;6-Aminoisocytosine;6-Hydroxy-2,4-pyrimidinediamine;NSC 44914;NSC 680818;NSC9302;
Waiwai Kemika o 2,4-Diamino-6-hydroxypyrimidine
● Nānā/Kaula:paʻa keʻokeʻo
● Pumi mahu:0.00232mmHg ma 25°C
● Lae hehee:285-286 °C (Dek.)(kumu)
● Hōʻike Hōʻikeʻike:1.7990 (manaʻo)
● Puni paila:288.5 °C ma 760 mmHg
● PKA:10.61±0.50(Wanamua)
● Lae Uila:128.3 °C
● PSA：98.05000
● Māmā:1.84 g/cm3
● LogP:0.50900
● Mahu Waihona: E hoʻomaloʻo ma +4°C
● Pilikino.: Māmā
● Solubility.:DMSO (Lili iki), Methanol (Lili iki)
Maʻemaʻe/Maʻemaʻe
99% *ʻikepili mai nā mea hoʻolako maka
2,4-Diamino-6-hydroxypyrimidine *ʻikepili mai nā mea hoʻolako reagent
ʻIkepili palekana
● Piktogram(s):
Xi
● Nā Code Hazard:Xi
● ʻŌlelo:36/37/38
● ʻŌlelo Palekana:22-24/25-36-26
Nā waihona MSDS
Pono
● Hōʻike: 2,4-Diamino-6-hydroxypyrimidine (DAHP) he mea koho, paʻa paʻa o GTP cyclohydrolase I, ka pae palena palena no ka de novo pterin synthesis.Ma nā pūnaewele HUVEC, ʻo ka IC50 no ka pale ʻana i ka biosynthesis BH4 ma kahi o 0.3 mM.Hiki ke hoʻohana ʻia ka DAHP e ālai pono i ka hana NO ma nā ʻano kelepona.
● Hoʻohana: 2,4-Diamino-6-hydroxypyrimidine (DAHP) he mea koho, mea hoʻopaneʻe kikoʻī o GTP cyclohydrolase I, ka pae palena palena no ka de novo pterin synthesis.Ma nā pūnaewele HUVEC, ʻo ka IC50 no ka pale ʻana i ka biosynthesis BH4 ma kahi o 0.3 mM.Hiki ke hoʻohana ʻia ka DAHP no ka hoʻopaʻa pono ʻana i ka hana NO ma kekahi mau ʻano kelepona. ʻO 2,4-Diamino-6-hydroxypyrimidine (cas # 56-06-4) he mea hoʻohui pono i ka synthesis organik.
ʻO 2,4-Diamino-6-hydroxypyrimidine he mea hoʻohui kemika me ke ʻano mole mole C4H6N4O.Hoʻohana maʻamau ia ma ke ʻano he intermediate i ka synthesis o nā pūhui like ʻole, me nā lāʻau lapaʻau a me nā dyes. ʻO ka pūhui he pyrimidine ring structure i loaʻa i ʻelua mau pūʻulu amino (NH2) a me hoʻokahi hui hydroxyl (OH) i hoʻopili ʻia i nā ʻāpana kalapona like ʻole.ʻO kēia hoʻolālā e lilo ia i mea paʻa hale no ka hoʻohui ʻana i nā molekole paʻakikī.2,4-Diamino-6-hydroxypyrimidine hiki ke loaʻa i nā ʻano hana synthetic, me ka hopena o ka cyanamide me ka urea.Loaʻa iā ia kekahi mau noi i ka ʻoihana lāʻau lapaʻau, ʻoi aku ka nui o ka synthesis o nā lāʻau anticancer a me nā lāʻau antibiotics. ʻO ka holoʻokoʻa, 2,4-Diamino-6-hydroxypyrimidine he mea koʻikoʻi e loaʻa ai ka pono i nā noi kemika a me nā lāʻau lapaʻau.
